Li Ma’s study titled “Mesenchymal Stem Cell-Originated Exosomal circDIDO1 Suppresses Hepatic Stellate Cell Activation via the miR-141-3p/PTEN/AKT Pathway in Human Liver Fibrosis” also points out that in vitro experiments can precisely control experimental conditions and further study intracellular molecular mechanisms, providing a erotica basis for in vivo experiments. The gene discussed is AKT1; the disease is Hepatic fibrosis.