However, cinnamaldehyde treatment significantly reduced the protein expression of p-TAK1, p-p38MAPK and p-NF-κB in the myocardium of rats with ventricular arrhythmias, which indicates that by regulating the TAK1 signalling cascade, cinnamaldehyde downregulates p-NF-κB expression, suppresses NLRP3 activation and protects ventricular arrhythmia rats from myocardial injury. The gene discussed is NLRP3; the disease is Ventricular arrhythmia.