Human DC2/moDC and TAM signatures were generated based on our scRNAseq (Fig. 5 G) and correlated with three Treg-associated genes (i.e., FOXP3, CTLA4, and TIGIT) in patients undergoing RT of radioresistant tumors (i.e., melanoma, glioblastoma, and head and neck cancer). The gene discussed is CTLA4; the disease is melanoma.