We repeated hemodynamic measurements and CF-related CVDrisk factors (Atherosclerosis risk factors: Fasting blood sugar, lipid profiles, andHbA1c) and systemic inflammation markers [C-reactive protein (CRP) and immunoglobulinG and pulmonary function tests] in children undergoing routine annual complicationevaluation and examined changes during follow-up. Here, CRP is linked to atherosclerosis.