MMP9 and esophageal cancer: For instance, MAGEA6 is highly transcribed and expressed in esophageal cancer, serving as a novel biomarker for diagnosis and treatment.[47] In gastric cancer, elevated MAGEA6 mRNA levels correlate positively with matrix metalloproteinase 9 (MMP‐9) expression, and higher MAGEA6 expression is associated with worse patient prognosis.