During AKI, renal immune and intrinsic cells produce numerous pro‐inflammatory cytokines, namely IL‐6, IL‐8, IL‐1β, TNFα, and TNF‐γ, as well as anti‐inflammatory cytokines at the site of inflammation, such as IL‐4, IL‐10, IL‐13, and TGF‐β. The gene discussed is TNF; the disease is acute kidney injury.