IFNA1 and acute kidney injury: This causes TECs separation, tubule obstruction, and function deterioration.[32] In clinical practice, an elevated production of IFN‐α is often noted in kidney biopsies from patients experiencing AKI after kidney transplantation.[29] Plasmacytoid dendritic cells (PDCs) are a unique subset of dendritic cells specialized in the production of interferon (IFN).