HMGCR and hepatocellular carcinoma: Statins, which are inhibitors of HMGCR, have been used in the treatment of various cancers, including HCC [120, 121, 122], BC [123, 124, 125], epithelial ovarian cancer [126], lung cancer [127], glioma [128], and colorectal cancer(CRC) [129], where the combination of statins and chemotherapy has been shown to enhance anti‐tumor effects [161] (Table 1).