The authors used avasimibe to inhibit sterol O‐acyltransferase (SOAT) and shRNA lentivirus to knock down SOAT1 expression, inhibiting SREBP1 activity, significantly reducing cholesteryl ester (ce) levels in GBM cells and decreasing lipid droplet (LD) formation [105]. Here, SOAT1 is linked to glioblastoma.