In tumor‐bearing mice (tumor cell lines: RMA, B16, and TrampC1), blocking cholesterol synthesis or inactivating the LXR‐α ligand by expressing SULT2B1b (a cholesterol sulfotransferase that converts oxysterols to inactive sulfated oxysterols) can restore DC function and enhance anticancer responses [225]. Here, NR1H3 is linked to neoplasm.