However, primary tumors can also exhibit a CINhigh phenotype, relying on a protective role of the inflammatory response, with a CIN‐driven inflammation important for tumor survival and growth.[27] Breast cancer cells with a CINhigh phenotype demonstrated a higher expression of NC NF‐κB genes, indicating higher treatment resistance. Here, NFKB1 is linked to cervical squamous intraepithelial neoplasia.