STING1 and cervical squamous intraepithelial neoplasia: This, in turn, promotes cytokine and chemokine production, enhancing the recruitment of immune cells into the TME.[13, 15] Nevertheless, DNA from MN can maintain CIN and lead to metastasis.[33a] In primary tumors STING activation is mostly associated with the switch of M2 into M1 macrophages,[42b] the activation of DCs, and subsequently T cell activation, supporting an anti‐tumoral immune response.[14, 15] However, it is important to note that in more advanced stages, particularly in the metastatic setting, it becomes increasingly challenging.