NPPB and pulmonary arterial hypertension: Moreover, Frantz et al, in a large study based on data from REVEAL, demonstrated that in PAH, baseline BNP levels (≤340 pg/ml and >340 pg/ml) strongly predicted survival up to 5 years, and BNP level changes from latest assessment within 1- and 5-years postenrollment to baseline correlated with the mortality risk.33