Notably, GAD1 exhibited the strongest association with CESD10 (“Having good sleep quality”) within the depression community (edge = 0.080); CESD1 demonstrated the most robust connection with GAD1 (“Feeling anxious, worried, or distressed”) within the anxiety community (edge = 0.030); and GAD3 was most strongly linked to CESD3 (“Feeling depressed or down”) within the depression context (edge = 0.031). This evidence concerns the gene GAD1 and depressive symptom measurement.