Similarly, Model 2 featured stone density (p < 0.001, OR = 6.12, 95%CI = 3.11–12.07), operation time (p = 0.004, OR = 2.18, 95%CI = 1.29–4.01), hydronephrosis (p < 0.001, OR = 0.35, 95%CI = 0.21–0.58), urine leukocytes (p = 0.025, OR = 1.91, 95%CI = 1.08–3.38), and the percentage of Tph cell (p < 0.001, OR = 0.38, 95%CI = 0.26–0.54) (Table 4). The gene discussed is TPH1; the disease is hydronephrosis.