Treatment with ET124 did not counteract TNF but led to a significant decrease in NOS1 (p < 0.05 vs. AD) and to less defective DLG4 and SYP mRNAs, together with a small significant increase in S100B (p < 0.05 vs. AD), suggested to be an Aβ42 suppressor (Cristóvão et al., 2018). The gene discussed is DLG4; the disease is Alzheimer disease.