Beneficial outcomes from ET124 addition to the AD triculture were noticed on the sustained expression of TREM2 near the control levels (p < 0.05 vs. AD) and on a slight effect on HLA-DRA and HMGB1 mRNAs (p = 0.07 and p = 0.1 vs. control, respectively). This evidence concerns the gene TREM2 and Alzheimer disease.