PPARA and Disorder of lipid metabolism: Previous researchers have demonstrated that Ampk, an energy switch, can enhance lipid degradation by up-regulating the Ppar-α and Cpt-1 protein expression, and inhibit de novo lipid synthesis through down-regulating the Srebp-1c (Smith et al., 2016; Herzig and Shaw, 2018), indicating FFDZ may improve lipid metabolism disorders by up-regulating p-Ampk expression.