IL6 and viral infectious disease: The cell senescence caused by viral infection forms a vicious cycle through the secretion of inflammatory mediators such as IL6 by SASP, while Shuanghuanglian may enhance the anti-apoptotic ability of senescent cells by up-regulating the expression of BCL2, promote the specific clearance of immune cells, and inhibit the IL6-mediated paracrine aging effect (60).