IL1B and Alzheimer disease: On the other hand, CI-AD group was characterized by higher levels of LPS (+24.7%), sVCAM-1 (+22.7% vs CU), sPECAM1 (+97.4% vs CU), sICAM-3 (+97.2% vs CU), and the pro-inflammatory cytokine IL-1β (+28.9% vs. CU), and lower levels of the anti-inflammatory cytokine IL-10 (−22.9% vs. CI-NAD).