NEFL and Alzheimer disease: Similarly, when considering MGBA mediators and neurodegenerative markers, higher levels of sP-Selectin (+82.2% in CI-NAD, +183.4% in CI-AD), sCD44 (+30.3% in CI-NAD, +39.8% in CI-AD), TNFα (+21.1% in CI-NAD, +18.7% in CI-AD), and NfL (+46.6% in CI-NAD, +69.1% in CI-AD) were reported in both CI groups compared to CU.