In advanced HF, high plasma Tie2 levels decreased after HT at 4 weeks and 6 months vs before HT, (p < 0.01, FDR = 1%), whereas low plasma PlGF preoperatively increased at 4 weeks and 6 months vs before HT (p < 0.0001, FDR = 1%), Table 3. This evidence concerns the gene TEK and hydrops fetalis.