In previous studies, we investigated plasma inflammatory and vascular growth factors related proteins, with focus on tyrosine kinases, in the context of HF and related PH, before and 1 year after HT, using a relative quantification method.9, 10 We found several candidate biomarkers of prognostic and hemodynamic importance, including Interleukin (IL)-6 and vascular endothelial growth factor-D (VEGF-D), the latter appearing to be involved in lymphangiogenesis and possibly pulmonary congestion and vascular remodeling.9, 10, 11, 12. This evidence concerns the gene VEGFD and hydrops fetalis.