The Folliculin (FLCN) gene, identified in 2002, is responsible for Birt-Hogg-Dubé (BHD) syndrome, an autosomal dominant genetic disorder characterized by fibrofolliculomas, pulmonary cysts, increased spontaneous pneumothorax frequency, and bilateral multifocal renal tumors (Blenis, 2017; Hardie, 2011). The gene discussed is FLCN; the disease is pneumothorax.