Alzheimer’s disease (AD) stands out as the leadingcauseof dementia and globally ranks as the seventh most significant causeof mortality.−,  The primary hallmark of AD is the formation of extracellularamyloid plaques in various regions of the brain. These plaques originate from the aggregation of amyloid-β(Aβ) peptides, which are produced through the cleavage of amyloidprecursor protein (APP).−, , ,  Among the different variants of Aβ peptides, those with 40and 42 residues (Aβ-40 and Aβ-42) are the most abundantand toxic, respectively.−, , , , , , , ,. This evidence concerns the gene APP and early-onset autosomal dominant Alzheimer disease.