In line with this, in children from Henan, China, after the COVID-19 pandemic, the children seropositive for EBV IgM (as a marker of PI) and EBV IgG (as a marker of HC) decreased in all age ranges, indicating that the COVID-19 pandemic reduced the infection of EBV in children in this population, suggesting a relation with the strict measures taken during the COVID-19 pandemic, such as suspension of classes, increased awareness of wearing masks, and paying attention to hand hygiene [14]. The gene discussed is CD40LG; the disease is infection.