GCH1 and non-small cell lung carcinoma: The results of the mitochondrial membrane potential assay with TMRE staining revealed that GCH1 overexpression significantly restored inhibition of mitochondrial membrane potential after GNA treatment (Figure 8J,K), suggesting that GCH1 overexpression reversed the inhibitory effects of GNA against malignant progression of NSCLC by regulating ferroptosis.