Interestingly, GSTM3 was found to confer radiosensitivity to nasopharyngeal carcinoma cells in vitro by inhibiting the expression of GPX4 and influencing the production of PUFAs by indirectly increasing polyunsaturated fatty acid production via fatty acid synthase (FASN) enzyme stability. The gene discussed is GSTM3; the disease is nasopharyngeal carcinoma.