Recently, nanocomplexes of diethyldithiocarbamate (DE), an inhibitor of aldehyde dehydrogenase 1A1 (ALDH1A1), conjugated with ferrous oxide nanoparticles (FeO NPs), demonstrated remarkable efficacy by inhibiting the growth, chemoresistance, and radioresistance of glioblastoma CSCs. The gene discussed is ALDH1A1; the disease is glioblastoma.