In the hepatocellular carcinoma model established by nitroso diethylamine, ART markedly suppressed the levels of Alkaline Phosphatase (ALP), Aspartate Aminotransferase (AST), Alanine Aminotransferase (ALT), LDH, and the pre-tumor marker g-GT, as well as decreasing the levels of IL-6, JAK-2, STAT-3 (pY705), Bcl-xL, and Bcl-2 expression and upregulating the levels of caspase-3 expression. Here, STAT3 is linked to hepatocellular carcinoma.