TLR4 and hydrops fetalis: In a carbon tetrachloride-induced animal model of HF, ART could inhibit the upregulation of TLR4, α-SMA, TGF-β1, and Myeloid Differentiation Factor (MyD88) at both the protein and mRNA levels and reduce the production of pro-inflammatory factors TNF-α and IL-6, as well as significantly inhibiting the levels of NF-κB p65.