Labeling proliferative cells targeting the ki-67 (MKI67) nuclear protein, which is encoded by the MKI67 gene and exclusively expressed in cells that are in a cell cycle state outside of G0, it is feasible not only to determine the character of a neoplasia (benign/malignant), but also to determine the degree of differentiation (grading) in various tumor entities [2,3,4,5,6]. Here, MKI67 is linked to neoplasm.