Hereby, only one group reported a statistically significant association, namely when analyzing the connotation between ki-67 staining pattern and lymph node metastasis (rho = 0.388, p = 0.0001; Spearman’s Rho and Cox Model) in relation to patient survival data [54], whereas all other studies confirmed no association. Here, MKI67 is linked to metastatic malignant neoplasm in the lymph nodes.