Changwan Ryu et al. identified a proteomic profile in plasma samples from patients with SSc-ILD associated with platelet activation, cell adhesion, and immune responses, with IGLV3-19 being one of the thirty-eight proteins whose levels differed from healthy controls (upregulated, log 2-fold change 1.90) [36]. Here, IGLV3-19 is linked to interstitial lung disease.