TGFB1 and idiopathic pulmonary fibrosis: Using a 3D hydrogel model that mimics the physico-chemical features of the interstitial matrix, including the fibrous mechanical cues and adhesive ECM ligands (including matricellular protein-mimicking Arginine–Glycine–Aspartic acid (RGD) and fibrous collagen-mimicking Glycine–Phenylalanine–Hydroxyproline–Glycine–Glutamic acid-Arginine (GFOGER) peptides), they showed that lung fibroblasts stimulated with canonical pro-fibrotic growth factor TGF-β resembled the transcriptional profile of IPF-specific myofibroblasts observed in patients.