BRCA1 and breast carcinoma: According to the National Comprehensive Cancer Network (NCCN), the risk-reducing salpingo-oophorectomy (RRSO) and the risk-reducing bilateral mastectomy (RRBM) can decrease the lifetime risk of developing ovarian cancer by more than 95% and breast cancer by 85–90% in patients carrying BRCA1/2 mutations [4,5].