GPT and obesity due to melanocortin 4 receptor deficiency: In a recent scientific report published in nature, Yang et al. report a negative correlation between magnetic resonance imaging-proton density fat fraction (MRI-PDFF), aspartate aminotransferase (AST), alanine aminotransferase (ALT), body mass index (BMI) as well as obesity class and Faecalibacterium [41].