CD4 and pulmonary tuberculosis: The mutual support between MTB and Cryptococcus, theoretically explained by the microbial IL10 production that reduces the Th-1 responses, could be practically sustained by Jarvis et al. in 2010: they concluded that a history of pulmonary tuberculosis within the last 2 years was independently associated with the development of Crypto-CNS (OR 6.6; 95%CI 1.3–32.7) after adjustment for covariates including CD4 counts [22].