CEACAM5 and gallstones: Age (≤58.5 vs. >58.5 years), size of GS (≤1.95 vs. >1.95 cm), course of GS (≤10 vs. >10 years), CEA (≤5 vs. >5 ng/mL), and CA 19-9 (≤37 vs. >37 U/mL) are independent risk factors for GBC in patients with GSs. When positive indicators were ≥2 among the five independent risk factors or the score of the nomogram was >82.64, the risk of GBC was high in gallstone patients.