Results: A very-LPD utilizing NFA showed significantly improved estimated glomerular filtration rate (MD, 1.00; 95% CI, 0.35–1.64, p = 0.002), reduced serum creatinine (MD, −0.44; 95% CI, −0.75 to −0.13, p = 0.006), decreased blood urea nitrogen (MD, −35.34; 95% CI, −64.27 to −6.42, p = 0.02), and lower parathyroid hormone levels (MD, −1.25; 95% CI, −2.33 to 0.18, p = 0.02) when compared to a standard LPD in patients with CKD. The gene discussed is PTH; the disease is chronic kidney disease.