Similarly, geniposide was found to inhibit NLRP3 inflammasome activation via autophagy in BV-2 microglial cells exposed to oxygen–glucose deprivation/reoxygenation, and to ameliorate dextran sulfate-induced colitis in mice via the Nrf2/HO-1/NF-κB pathway [53]. Here, NFKB1 is linked to colitis.