AKT1 and breast carcinoma: We also observed no change in Akt phosphorylation (P-Akt) after quercetin and an insignificant decrease after luteolin but an unexpected increase after G-1 treatment, which contrasts with the findings of Liu et al. (2022), who reported a decrease in P-Akt following G-1 treatment in SKBR-3 breast cancer cells [66].