PTGS2, an enzyme frequently overexpressed in various cancers [67], plays a crucial role in the synthesis of prostaglandins and thromboxanes, regulating processes key to cancer progression such as apoptotic resistance, increased cell proliferation, angiogenesis, inflammation, and the invasion and metastasis of cancer cells, significantly contributing to tumor growth and development [68,69]. This evidence concerns the gene PTGS2 and neoplasm.