To elucidate the molecular mechanisms by which Loureirin A and Loureirin B inhibit migration and invasion in NSCLC cells, we analyzed the activity of matrix metalloproteases (MMP-2 or gelatinase A and MMP-9 or gelatinase B) in culture supernatant using a gelatin zymography assay. Here, MMP2 is linked to non-small cell lung carcinoma.