Analysis of PFS revealed that high NCKAP1 expression in KIRC (p = 0.0038) and LGG (p = 0.018) correlated with improved prognosis, whereas high NCKAP1 expression in ACC (p = 0.005) and uveal melanoma (UVM, p = 0.032) was associated with poorer outcomes, which emphasized the importance of NCKAP1 as a biomarker for cancer survival and its impact on patient outcomes, suggesting its potential for personalized therapeutic approaches on the basis of gene expression profiles. This evidence concerns the gene NCKAP1 and uveal melanoma.