ABCA1 and cancer: To elucidate the critical importance of the tumor immune microenvironment in the initiation and progression of kidney malignancies, we investigated the relationship between NCKAP1 expression and the TME and demonstrated that the infiltration levels of 24 immune cell types in cancer were correlated with NCKAP1 expression via lollipop graph analysis (Figure 2A), which revealed a notable positive association between NCKAP1 and several immune cell types, including Tcm cells, neutrophils, mast cells, eosinophils, and Tgd cells.