Analysis of PFS revealed that high NCKAP1 expression in KIRC (p = 0.0038) and LGG (p = 0.018) correlated with improved prognosis, whereas high NCKAP1 expression in ACC (p = 0.005) and uveal melanoma (UVM, p = 0.032) was associated with poorer outcomes, which emphasized the importance of NCKAP1 as a biomarker for cancer survival and its impact on patient outcomes, suggesting its potential for personalized therapeutic approaches on the basis of gene expression profiles. The gene discussed is NCKAP1; the disease is cancer.