TGFB1 and neoplasm: Moreover, TNBC tumor cells secrete granulocyte-macrophage colony-stimulating factor (GM-CSF), TGF-β, and CXCR2 which stimulates TANs to release tumor suppressor M, promotes angiogenesis, and improves tumor cell infiltration or recruitment of neutrophils in TNBC [87,88,89].