STAT3 and neoplasm: In TNBC, miR expression is differentially regulated and associated with tumorigenesis or tumor suppression, for example, by targeting transmembrane 4 L6 family member 1 (TM4SF1), miR-206 affects cell migration and invasion in MDA-MB-231 TNBC cells [173], miR-340 also affect cell invasion and metastasis by targeting and inhibiting Rho Kinase 1 (ROCK1) [174], and miR-124 target STAT3 and STAT3 signaling and downregulates cell proliferation and invasion [175].