RT and anti-PD-L1 antibody or CTanti-CTLA-4 (9H10 monoclonal antibody) administration in mice reduced TNBC tumor growth and lung metastasis in animals, indicating that RT with blockade of PD-1 or CTLA-4 may be the effective strategy against TNBC metastasis [143,144]. This evidence concerns the gene CTLA4 and neoplasm.