This neoplasm originates from the precursors of plasmacytoid dendritic cells (pDCs) [2,3,4], which are a specialized subset of immune cells known for their role in the immune response, particularly through the secretion of interferon-alpha (IFN-α) during viral infections and a Th2 polarization following Interleukin-3 (IL-3) induction [1,2,5,6,7,8,9]. Here, IL3 is linked to neoplasm.