Susceptibility to T1DM in CVID has also been reported [106], and in a patient with a monogenic form of the disease, bearing a variant in the TNFRSF13C gene encoding for BAFF receptor (BAFFR), it was accompanied by severe immune dysregulation with ITP and peripheral polyneuropathy [107]. The gene discussed is TNFRSF13C; the disease is autoimmune thrombocytopenic purpura.