STAT3 and common variable immunodeficiency: The granulomatous lymphocytic interstitial lung disease (GLILD) is primarily ascribed to CVID, yet systemic excessive inflammatory response with granulomatosis was also assessed in other pediatric syndromic IEI disorders, such as hyper-IgE (STAT3-HIES), CDC42 deficiency [49], 22q11.2 deletion [50], and Nijmegen breakage syndrome [51].