Remarkably, DNMT1 is thought to be a cause of TNBC by hypermethylating the promoters of ER, several oncosuppressors, and EMT-related target genes (including CDH1, encoding for E-cadherin), thus promoting tumor growth, autophagy, and metastasis [51,52,73,85]. The gene discussed is DNMT1; the disease is neoplasm.