IGFBP6 and Behcet disease: The study mentioned in the SZ Section 4.4.3 detected that IGFBP-6 was significantly and negatively correlated with BD by the Linkage Disequilibrium Score Regression (LDSC) regression coefficient calculated from a large genome-wide association study (GWAS) conducted with 20,129 BD patients and 21,524 controls [98].