ABL1 and chronic myelogenous leukemia, BCR-ABL1 positive: Moreover, conventional cytogenetics or fluorescence in situ hybridization (FISH) and molecular tests are used to verify the presence of the Philadelphia (Ph) chromosome—the t(9;22)(q34;q11)—or the Ph-related molecular BCR::ABL1 abnormality, to diagnose typical CML [9].