To investigate the role of NF-κB in cervical lesion development, immunohistochemical analysis was conducted to examine the expression of the RELA of the NF-κB family in 38 cervical epithelial tissue samples at various pathological stages, including normal samples, simple hyperplasia, CIN1, CIN2, CIN3, and CSCC. Here, NFKB1 is linked to cervicitis.