GLP1R and familial pancreatic carcinoma: Furthermore, pancreatic ductal adenocarcinoma and pancreatic intraepithelial neoplasia, both associated with pancreatic cancer development, express GLP-1R, while normal pancreatic ductal cells and acini demonstrate proliferative responses to GLP-1RAs, suggesting that incretin-based medications may induce specific proliferative changes in the islets.