To sum up, age greater than 53 years, BMI greater than 25, TC greater than 5.6 mmol /L (100.8 mg/dl), ApoB value greater than 0.9 g/L, TG greater than 1.4 mmol /L(124.2 mg/dl), hypertension, TP greater than 81 g/L, HDL_C lower than 1.2 mmol /L(46.4 mg/dl), WBC greater than 6.2 × 109 /L may be the risk factors for pre-diabetes. The gene discussed is APOB; the disease is diabetes mellitus.