PMP22 and hereditary neuropathy with liability to pressure palsies: CNVs shown in patients with CMT1A, HNPP, PTLS and SMS are commonly related with nonallelic homologous recombination (NAHR)-mediated recurrent rearrangements involving low-copy repeat (LCR) sequences, while CNVs of the most YUHAL and MDS cases are associated with nonrecurrent replication-based fork stalling and template switching/microhomology-mediated break-induced replication15.