SIRT3 and neoplasm: The carcinogenesis phenotype was evaluated by the proliferation assessment and the analysis of gene expression of representative genes involved in carcinogenesis such as tumor suppressor genes (BRCA1, PTEN and TP53) and genes related to antioxidant protection (SIRT1, SIRT3, SIRT6 and GSTM2) as tumor-protecting genes and a group of tumor-promoting genes (BIRC5, MYC and ALDH3A1).