0.318–1.515 mg/kg DON decreased the glucose concentration in middle intestine. The effects on mRNA and protein expression suggest impaired immune function in intestines.0.636–1.515 mg/kg DON increased enteritis morbidity after infection with Aeromonas hydrophila and decreased activities of lysozyme and acid phosphatase, as well as content of IgM, complement 3, and complement 4 in intestines. This evidence concerns the gene LYZ and infection.