CASP4 and infection: The expression of nine proteins (MCP-1, CCL3, CCL4, CCL20, CXCL1, IL-8, CXCL9, CXCL10, and CXCL11) were identified as being significantly altered after HK1651 infection compared to unstimulated Cas9 and/or caspase1- and caspase-4-deficient cells (Figure 2).