The protein expression of seven proteins (CD8A, ST1A1, AXIN1, FGF-5, MMP-10, HGF, SIRT2) was significantly decreased and the protein expression of two proteins (MMP-1, TNFRSF9) was significantly increased in caspase-1-deficient cells compared to Cas9 cells following HK1651 infection (Figure 3). This evidence concerns the gene CD8A and infection.