CCL2 and ocular toxoplasmosis: Similar studies using CCL2 blockade in mouse ocular toxoplasmosis have not been reported; however, mice with chronic T. gondii encephalitis present decreased brain infiltration of monocytes, neutrophils, and CD4- and CD8-positive T cells, with increased parasite burden, when the animals’ astrocytes are rendered Ccl2-deficient [79].