MAPT and early-onset autosomal dominant Alzheimer disease: Also, the neurotoxicity mechanism of ZnCl2 exposure was previously demonstrated by Sarasamma et al. Their findings suggest that even at low concentrations, zinc induces decreases in phosphorylated Tau (p-Tau) and amyloid beta (amyloid β) protein levels, proteins that are also used as biomarkers in Alzheimer’s disease.